TRANSLATION AND CROSS-CULTURAL ADAPTATION OF THE SUPPORTIVE AND PALLIATIVE CARE INDICATORS TOOL INTO JAPANESE: A PRELIMINARY REPORT

Translation and Cross-Cultural Adaptation of the Supportive and Palliative Care Indicators Tool into Japanese: A Preliminary Report

Background: There is a need for tools in primary care to support clinicians to identify patients with unmet palliative care needs.The Pants Supportive and Palliative Care Indicators Tool (SPICT) is concise and covers most conditions in primary care settings.However, the SPICT was not available in Japanese.Methods: The translation and cultural adapt

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Clostridioides difficile toxin B subverts germinal center and antibody recall responses by stimulating a drug-treatable CXCR4-dependent mechanism

Summary: Recurrent Clostridioides difficile infection (CDI) results in significant morbidity and mortality.We previously established that CDI in mice does not protect against reinfection and is associated with poor pathogen-specific B cell memory (Bmem), recapitulating our observations with human Bmem.Here, we demonstrate that the secreted toxin Tc

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